Top AI startups in San Francisco
1,567 AI-native startups are based in San Francisco, 19 of them valued at $1bn or more. 1,137 were founded in the last three years.
- 1DeelThe all-in-one HR and payroll platform for global teams$17.3bn

- 2Scale AIData-centric infrastructure to accelerate the development of AI $29bn

- 3FaireThe global online platform empowering independent retail.$12.6bn

- 4PerplexityAnswer engine that cites its sources.$20bn
- 5CheckrPeople infrastructure for the future of work$4.6bn

- 6Cognition AIArtificial Intelligence. Valued at $48bn (September 2026).$48bn

- 7VantaVanta—the proven leader in automated compliance helping startups…$1.6bn

- 8HarveyGenerative AI built for law firms and in-house teams.$15.5bn

- 9CorgiCorgi is building an AI financial infrastructure company$1.3bn

- 10AirbyteThe open standard in data connectivity for AI and analytics.$1.5bn

- 11MercorArtificial Intelligence. Valued at $10bn (October 2025).$10bn

- 12VercelCloud computing / AI. Valued at $9.3bn (September 2025).$9.3bn

- 13HappyRobotIntelligence that runs your operations. $1.2bn

- 14Together AIArtificial Intelligence. Valued at $8.3bn (July 2026).$8.3bn

- 15HiggsfieldArtificial Intelligence. Valued at $5.4bn (August 2026).$5.4bn

- 16GongArtificial intelligence. Valued at $4.5bn (November 2025).$4.5bn

- 17GammaArtificial intelligence. Valued at $2.1bn (November 2025).$2.1bn
- 18CrestaReal-time AI for contact centre agents.$1.6bn
- 19SiftThe Leader in Digital Trust & Safety$1bn

- 20AmplitudeDigital Analytics PlatformPublic

- 21MatterportTurn physical objects and environments into 3D models in seconds.Public

- 22PrestoDigital meets physical for big chain restaurantsPublic

- 23Unsloth AIOpen-Source Reinforcement Learning (RL) & Fine-tuning for LLMs.Early stage

- 24NanoNetsAutomatic Data ExtractionGrowth

- 25HackerRankChange the world to value skills over pedigreeGrowth

- 26RescaleHigh Performance Computing Built for the CloudGrowth

- 27GrubMarketAI-powered technology enabler and digital transformer of American…Growth

- 28AiSDRAI that finds the right buyers and books sales meetingsEarly stage

- 29AthelasExtensible, Integrated Technology that Simplifies Health SystemsGrowth

- 30IroncladAI-powered contract managementGrowth

- 31TomaAI Applied ResearchGrowth

- 32Pair TeamBuilding the safety net of the futureGrowth

- 33TRM LabsTRM is building a safer world for billions of people.Early stage

- 34People.aiHarnesses business activity to unlock growth.Growth

- 35ScribdWorld's largest online library.Growth

- 36SendbirdThe AI agent that doesn’t just support, it delights.Growth

- 37HumandAll-in-one app for internal communication and HREarly stage

- 38TeleportThe Infrastructure Identity CompanyGrowth

- 39Observe.AIContact center AI platform.Growth

- 40QventusWe automate operations for hospitals and health systemsGrowth

- 41JerryJerry is building the AI agent to manage all your physical assets.Growth

- 42FieldguideVertical AI for Audit & Advisory FirmsGrowth

- 43HightouchThe leading Composable CDP and AI Decisioning platformGrowth

- 44Pibit.aiThe AI Underwriting OS for Commercial, Specialty & E&S insuranceGrowth

- 45LumariAI Digital Workers for Supply Chain Early stage

- 46Focal SystemsBuilding the Operating System for B&M Retail using Deep LearningGrowth

- 47TempoLive home fitness training powered by computer vision.Growth

- 48Nozomiocreators of folk.comEarly stage

- 49Ambient.aiAI company transforming enterprise physical security to prevent…Growth

- 50GigsThe OS for Embedded TelecomGrowth

The top 50 of 1,567. Everything else is on the San Francisco page.
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How this list is ranked
By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.