Top AI startups in Melbourne
11 AI-native startups are based in Melbourne. 8 were founded in the last three years.
- 1Mindset HealthBuilding AI therapeutics for physical health conditions like IBS.Growth

- 2BIXSOAustralian business-AI company founded 2017 in Melbourne; creator of the Business Solution Canvas.Founded 2017

- 3CartesianAustralian software company for AI agent distribution.Founded 2024

- 4Empirica TechnologiesAustralian technology company based in Melbourne, providing AI-driven data-process and decision-grade data-design services; registered as Empirica Technologies Pty Ltd (ABN 76 698 226 247).Founded 2026

- 5ExpandIQAustralian artificial intelligence transformation and consulting company.Founded 2025

- 6HOOKiQAustralian AI audience simulation platform that generates synthetic personas and predicts marketing reception.Founded 2026

- 7KoalaFixAustralian software company making shared memory for AI coding agents.Founded 2026

- 8MasterKeyAustralian hotel management AI software company.Founded 2026

- 9altanicheAustralian AI security, governance and training company.Founded 2024
- 10Briefdots Pty LtdAustralian artificial intelligence consultancy based in Melbourne.Founded 2021
- 11ModernModern automates the entire order-to-cash process for B2B companies.Early stage

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How this list is ranked
By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.