Cambridge · updated 13 November 2026

Top AI startups in Cambridge

12 AI-native startups are based in Cambridge. 3 were founded in the last three years.

  1. 1
    ReactWise logo
    ReactWiseAI Co-Pilot for Chemical Process OptimizationEarly stage
  2. 2
    Resseti logo
    RessetiBritish educational technology company.Founded 2024
  3. 3
    Cambium AI logo
    Cambium AIPublic data describes populations one column at a time. Cambium AI puts the people back, so any team can ask about who actually exists.Founded 2025
  4. 4
    Ever Resource logo
    Ever ResourceFounded 2020
  5. 5
    Ignota Labs logo
    Ignota LabsIgnota Labs is the AI drug turnaround company. We find out why promising drugs failed on safety and re-engineer better versions for the clinic.Founded 2021
  6. 6
    Luminance logo
    LuminanceLegal-grade AI for contract negotiation.
  7. 7
    Nuclera logo
    NucleraRapid protein prototyping, making proteins accessible — it’s what we do. It’s what we deliver. Click here to learn more.Founded 2013
  8. 8
    Shift Bioscience logo
    Shift BioscienceFounded 2017
  9. 9
    Transition Bio logo
    Transition BioSolving the Unsolvable Redefining drug discovery at the molecular level By combining the technology and data engine of Harvard’s Weitz Lab and the…Founded 2020
  10. 10Founded 2019
  11. 11Founded 2011
  12. 12Founded 2021

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How this list is ranked

By a notability score built from public facts: valuation, a stock market listing, open-model downloads on Hugging Face, team size, a Wikidata entry and a verified owner. Nobody pays to rank higher. Rebuilt every morning. Methodology · Is your company here? Claim it.